Tetraoxo derivatives of perhydropyrrolo[3,4‐c]pyridine

Michael adducts from diethyl fumarate with malonic esters or nitriles were cyclized to succinimide intermediates which, after glutarimide ring closure, afforded several N-methyl and N-benzyl derivatives of cis-1,3,4,6-tetraoxoperhydropyrrolo[3,4-c]pyridine whose configuration was demonstrated by X-ray crystal structure analysis.