Analysis of the ratio of mitchondrial DNA with A1555G mutant to wild type in deaf patients of Fujian province in China by a new method and its relationship with the severity of hearing loss
2011
背景变异、野的类型 mitochondrial DNA 的比率可能与它的临床的 phenotype.In 有关,这被建议了这研究,我们开发了高敏感的即时扩大倔强的变化为 mitochondrial DNA ( mtDNA )与的 quantitation 的系统量的聚合酶链反应( RT-ARMS-qPCR )试金一变异 1555 地点,并且探索了在变异的 mtDNA 的比率和听见 mitochondrial 聋( MD )的损失的严厉之间的关系福建 pr 的病人
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