Effects of ospemifene, a novel selective estrogen-receptor modulator, on human breast tissue ex vivo.

AbstractObjective:Ospemifene (Osp) is a novel selective estrogen-receptor modulator (SERM) accepted for the treatment of dyspareunia, a symptom of postmenopausal vulvovaginal atrophy. We aimed to analyze the effects of Osp on human breast tissue (HBT), in comparison with the clinically established S