PULSED ULTRASOUND COMBINED WITH ACOUSTIC PHASE-CHANGE NANOPARTICLES DISSOLVE PORCINE CORONARY ARTERY THROMBUS IN VIVO

The culprit coronary artery in acute myocardial infarction (AMI) were occluded and caused myocardial ischemia. Based on stable cavitation, we sought to investigate a novel phase-change contrast agent (perfluoropentane-loaded nanoparticles, PFP@NPs) for the treatment using AMI porcine model. 9