Serum visfatin in Asian women with polycystic ovary syndrome

Objective. To determine serum visfatin levels in Asian polycystic ovary syndrome (PCOS) women and its correlations with various parameters.Study design. Case–control study.Setting. University hospital.Subjects. Eighty women were enrolled in this study. Of these, 40 women were PCOS and 40 age-matched subjects with regular menstrual cycles were controls.Intervention. Seventy-five gram oral glucose tolerance tests were performed in all women. Fasting venous blood samples for serum visfatin, insulin and androgen levels were obtained both from the PCOS and the control women.Main outcome measures. Serum concentrations of visfatin, fasting insulin (FI), fasting glucose, 2-h post-load glucose (2hPG), homeostasis model assessment insulin resistance, homeostasis model assessment beta cell function, total testosterone, free testosterone, androstenedione and dehydroepiandrosterone sulfate were measured in both groups.Results. Women with PCOS had significantly higher serum visfatin levels than the healthy controls [10...