PHENYTOIN INDUCED ERYTHEMATOSUS RASH IN A DIABETIC SEIZURE PATIENT

Article history This is a case report of 1 year old male patient, who has experienced rashes after the use of phenytoin for the treatment of seizures. The blood glucose level of the patient was high, which may have triggered seizure in the patient. This type of seizure is known as diabetic seizure. Phenytoin is a hydantoin compound related to the barbiturates that are used for the treatment of seizures. It is one of the most commonly used anticonvulsant drugs. These drugs frequently cause cutaneous eruptions, especially during inception of new therapy. In addition to causing common and usually limited morbilliform and urticarial eruptions, which have often mild morbidity. In this case, the patient has developed erythematosus rash all over the body on the fifth day after administration of phenytoin. This ADR (Adverse drug reaction) has scored 6 points on naranjo scale of causality assessment. The possible reason for the adverse drug reaction was found to be the drug over-dose.