Pathological impairments induced by interstitial implantation of 125 I Seeds in spinal canal of

Background: Use a banna mini-pig to set up 125I implantation model, and investigate the consequence of radiation-related impairments. Methods: In present study, 125 I seeds were implanted into spinal canal of T13 level of spine in banna mini-pigs. After operation, the pigs were raised up to 8 months, behavior changes were recorded within this period. After 8 months, spinal cords were collected for pathological analysis. Results: In this study, a 125 I brachytherapy animal model had been successfully established, in the model group,