CONTRIBUTION OF NMR SPECTROSCOPY, MASS SPECTROMETRY AND X-RAY DIFFRACTOMETRY TECHNIQUES TO THE CHARACTERIZATION OF 2-CHLORO-8-METHYL-3-FORMYLQUINOLINE

Quinoline and its analogues have been known to possess diverse pharmacological activities. In the last three decades 2-chloro-8-methyl-3-formylquinoline has been utilized as building blocks for the development of various quinolines fused heteroaryl rings. In this article we report the complete spectral details of 2-chloro-8-methyl-3-formylquinoline. The techniques involved in the characterization of title compounds are various NMR experiments such as HSQC, COSY and HMBC. Molecular weight was determined by FAB-mass spectrometry. The powder XRD study revealed crystal behavior of the title compound.