[Clinical and pathological analysis of 114 cases with non-ductal pancreatic adenocarcinoma occupying lesions].

Objective To improve the diagnosis and treatment of non-ductal pancreatic adenocarcinoma-occupying lesions.Methods A retrospective analysis was made for 114 cases of pancreatic non-ductal adenocarcinoma-occupying pathologically confirmed lesions.Results ①There were 36 males (31.6%)and 78 females(68.42%);②presenting symptoms and signs were abdominal pain(n=56,49.1%),back pain(n=24,21.1%),weight loss(n=18,15.8%)and obstructive jaundice(n=8,0.07%);③the positive rates of Cal9-9,CA242 and CEA were 21.1%,19.7% and 5.6%respectively;④pancreaticoduodenectomy was performed in 26 patients,distal pancreatectomy in 53,tumor enucleation in 15,segmental pancreatectomy in 9,partial resection in 3,duodenum-preserving pancreatic head resection in 1 and palliative surgery(either cholecystojejunostomy anastomosis or gastrojejunostomy)in 7;⑤pathologic analysis revealed 35 solid pscudopapillary neoplasm of pancreas,28 pancreatic endocrine tumors,18 focal hronic pancreatitis,11 serous cystic neoplasms,9 mucinous cystic neoplasms,4 pancreatic cysts,3 acinar cell carcinomas,2 pancreatic cavernous hemangiomas,1 sarcoma of pancreas,1 sarcomatied carcinoma of pancreas.1 pancreatic schwannnoma and 1 pancreatic neuroblastoma.Conclusion The non-ductal pancreatic adenocarcinoma-occupying lesions have no specific clinical presentation or serum tumor marker.An understanding of the natural history of these lesions is important for optimal management. Key words: Pancreas neoplasms; Occupying lesions; Clinical presentation; Treatment