The effects of health education and comprehensive lifestyle modification on postmenopausal osteoporosis women treatment with alendronate sodium

Objective To evaluate the effects of an intervention programme of health education and life style modification on postmenopausal osteoporosis women. Methods A total of 120 postmenopausal osteoporosis women were enrolled in this one-year randomized controlled follow-up study and assigned to the intervention group (Group A, n=60) or the control group (Group B, n=60). Both groups were treated with alendronate sodium.In Group A, education program was performed once a season in the form of face-to-face consultation or group session.In Group B, no additional intervention was used.The primary outcome was patients' compliance in follow-up.The secondary outcomes were change in bone mineral density (BMD). BMD was measured by dual-X-ray absorptiometry (DXA) on lumbar spine and hip at baseline and 12 months after the intervention. Results After one-year intervention, 51 subjects in Group A and 38 in Group B completed the follow-up.Groups A showed better compliance.BMD on lumbar spine and hip was significantly increased in both groups when compared with baseline.The changes of BMD on lumbar (0.042±0.067 vs 0.026±0.070, P=0.029) or Words region (0.029±0.129 vs 0.023±0.143, P=0.041) showed statistical significance between the two groups. Conclusion For alendronate sodium treatment, health management ensures the effectiveness of the therapy and improves the compliance of the patients. Key words: Osteoporosis; Bone density; Life style; Education; Health management