Autoimmune polyradiculopathy in SARS-CoV-2: A narrative review of guillainbarre syndrome in novel coronavirus disease (COVID-19)

Introduction: Novel Coronavirus Disease 2019 (COVID-19) is an infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which is believed to emerged from an animal source and had been spreading rapidly among the humans It has been declared as a global pandemic, with more than 14 million reported cases and more than six hundred thousand death worldwide to date Recently, there are evidence that show it exhibits neurotropic properties and cause neurological diseases Guillain- Barre syndrome (GBS) is the most common reported neurological syndrome that occur in COVID-19 patients This study attempts to determine the possibility of GBS in SARS-CoV-2 infection Materials and methods: In this article, we review all scientific paper of early reporting on GBS that occur in COVID-19 patients from 1st January 2020 to 1st July 2020 to study the possible pathophysiological mechanism and the common clinical features Results: SARS-CoV-2 infection can be associated with GBS in a more complex presentation Conclusion: This review aims to elucidate the involvement of autoimmune polyradiculopathy in SARS-CoV-2 infection and hopefully able to improve the management and prognosis of COVID-19