Carcinome épidermoïde Primitif de la Prostate: A propos d’un cas et revue de la littérature

Le cancer de la prostate est la tumeur maligne la plus frequente chez l’homme. La grande majorite des tumeurs de la prostate est representee par l’adenocarcinome prostatique (jusqu’a 95%). Le carcinome epidermoide primitif est tres rare et ne represente que 0,5% a 1% des carcinomes prostatiques. Jusqu’a 2014 seulement 24 cas ont ete decrits dans la litterature. Nous rapportons un nouveau cas de carcinome epidermoide primitif de la prostate chez un jeune âge de 48 ans diagnostique a un stade metastatique. Malgre une chimiotherapie a base de Cisplatine et Metoxantrone, le deces est survenu 2 mois apres le diagnostic. A travers cette observation et une revue de la litterature, nous discutons les differents aspects cliniques, histologiques, therapeutiques et pronostiques de cette tumeur. Mots cles: prostate; carcinome epidermoide; histologie; metastases; traitement multimodal English Title:  Primary squamous cell carcinoma of the prostate: a case report and review of literature English Abstract Prostate cancer is the most frequent malignant cancer in men, with the majority (nearly 95%) of prostate cancers being adenocarcinomas. Primary squamous cell carcinoma of the prostate is rare, representing only 0.5% to 1% of all prostatic carcinomas. Till 2014, only 24 cases have been published in the literature. We report a new case of primary squamous cell carcinoma of the prostate occurring in a young 48-years-old man and diagnosed at a metastatic stage. Despite of the chemotherapy based on Cisplatine and Meitoxantrone, death occurred two months after the diagnosis. Based on this observation and referring to literature review, we discuss the various clinical, histological, therapeutic and prognostic features of this rare tumour. Keywords: prostate; squamous cell carcinoma; histology; metastases; multimodal treatment