Paradoxical psoriasiform reactions to antitumour necrosis factor‐α drugs in hidradenitis suppurativa

Paradoxical psoriasiform reactions to anti-tumor necrosis factor α (TNFα) agents occur with an incidence of 0.3 to 5.6% in patients with inflammatory bowel diseases and rheumatic diseases1. Various clinical features have been described while histopathological findings often show lichenoid infiltrate, spongiosis associated with a psoriasiform pattern and a “type I interferon (IFN) signature “ in immunohistochemistry2 This article is protected by copyright. All rights reserved.