Evaluation of intestinal perfusion monitoring techniques

Persistent hypoperfusion of the intestinal mucosal is considered important for the development of systemic complications during critical illness. The mucosal circulation is however not readily accessible to quantitative measurements of perfusion. Measurements of systemic perfusion are often extrapolated clinically to reflect regional perfusion, including the gastrointestinal organs. This extrapolation may introduce errors in the evaluation of hemodynamic status. Furthermore, the complex variable of person involves movement of blood and erythrocytes as well as the exchange of carbon dioxide and oxygen.