Application of symmetry patterns to recognition of functional sites and phylogenetic analysis of DNA sequences
1998
The set of genetic texts, taking part in replication initiation has been analyzed from the point of view of their symmetry. The subsets, corresponding to the phenotypical classification, were found to contain the same symmetrical structures. Along with the traditional symmetries (potential hairpins, direct and inverted repeats) the purine-pyrimidine and aminoketo repeats were found at equal distances in related sequences. Among the symmetrical structures the replication protein binding sites have been identified as well as sites taking part in the transcription initiation. The results obtained show the efficiency of symmetrical analysis in solving the problem of pattern recognition in genetic text.
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