Evaluation of factors which determining survival of SARS COV-2 infected patients in intensive care unit

Background: The disease SARS-CoV-2, which started in Wuhan city of China and caused pandemic, created an increasing number of intensive care needs due to its severe respiratory failure. The factors that determine the course of patients followed in intensive care are different. Therefore, our aim was to determine the factors that predict mortality and affect prognosis by evaluating the patients admitted to our intensive care unit. Methods: This study is a single-center retrospective study involving 156 patients admitted to our Intensive Care Unit , who was diagnosed with SARS-COV-2 between 20 March and 8 June 2020. The data including characteristics, symptoms and laboratory findings of the patients were recorded and their relationships to mortality were evaluated Results: The mean age was 69 ± 15 years and 63% were male. The most common symptom was dyspnea (69.9%) and fever (60,9 %), respectively. Comorbidity was present in 82% and the most common comorbidity was HT and DM, respectively. All patients were admitted to the intensive care unit with (due to) hypoxemic respiratory failure. 106 patients (68.8%) were connected to mechanical ventilation, which was associated with mortality (p <0.0001). High flow oxygen therapy was delivered in 31 patients and was associated with survival (p <0.05). Tozulizumab, given in addition to the treatments increased the survival (p<0.05). Conclusion: We saw in our study that many parameters will be effective in predicting survival. As the most determining factors, not being intubated during admission and / or follow-up was observed to be effective on survival and was found to be associated with mortality.