Cyclosporine A delays wound healing and apoptosis and suppresses activin beta-A expression in rats

The interaction of immune cells and connective tissue plays an important role in various (patho)physiological conditions such as cutaneous wound repair or development of fibrosis in systemic sclerosis (scleroderma). Immunosuppressive agents, such as cyclosporine A (CsA), are widely used for prevention of rejection following organ or bone marrow transplantation as well as in a number of autoimmune diseases, including scleroderma. [...]