Serine-Threonine Kinase Receptor Associate Protein (STRAP) Confers Stemness in Neuroblastoma
2021
Background: Serine-threonine kinase receptor associated protein (STRAP) is a scaffolding protein that has been implicated in tumor growth and metastasis. The role of STRAP in neuroblastoma (NB) has not been explored. Stem cell-like cancer cells (SCLCCs) are believed to be responsible for tumor cell self-renewal and cancer recurrence. We sought to determine the role of STRAP in neuroblastoma SCLCCs maintenance. …
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