계피식물(Cinnamomum Loureiroi)에서 분리한 coumarin과 유도체의 방오효과

The active antifouling compounds coumarin and its derivatives were isolated fiom the cinnamon tree Cinnamomum loureiroi. The antifouling activities were determined using representative soft fouling organisms: the seaweed Ulvapertusa and diatom Navicula annexa. The chemucal constituents with antifouling activities were identified as coumarin, hydroxylcoumarin, coumaric acid, and cinnamaldehyde by interpreting nuclear magnetic resonance, and high-resolution mass spestroscopy data. These compounds were isolated from 1.09g of crude Cinnamomum sp, methanol extract, yielding approximately 18.4, 6.3, 9.8, and 14.7mg of coumarin, hydruxylcoumarin, coumaric acid, and cinnamaldehyde, respectively. The compounds inhibited U. Pertusa zoospores wich EC50 valwes of 0.13-0.25ug/mL, and the diatomN.annexa with EC50 of0.21-0.81ug/mL.