Achromic verrucous large cell acanthoma.

Large cell acanthoma (LCA) is an epidermal neoplasm whose nature has been variously explained. Though frequently hyper-pigmented, we describe for the first time an achromic case located on the dorsum of the right hand of a 83-year-old woman. This observation is largely inconsistent with one of the theories about the nature of this condition: that it is merely a solar lentigo with large nuclei of keratinocytes.