A single mutation 202G>A in the human glucose-6-phosphate dehydrogenase gene (G6PD) can cause acute hemolysis by itself

2002 
Glucose-6-phosphate dehydrogenase (G6PD) A-is a common G6PD variant among Africans that may cause acute hemolysis triggered by infections and certain drugs, as well as by fava beans. This class-3 phenotype can be caused by a combination of the common 376A>G (Asn126Asp) mutation and either of 3
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