This, too, shall pass—like a kidney stone: a possible path to prophylaxis of nephrolithiasis? Focus on “Cholinergic signaling inhibits oxalate transport by human intestinal T84 cells”

nephrolithiasis (kidney stones) has a lifetime prevalence in the developed world of ∼5% in females, and up to 12% in males, with recurrence in 50% of cases. Normal human urine is supersaturated with respect to the calcium oxalate ion pair, and roughly two thirds of kidney stones are composed