Interobserver variability of myocardial T1 and T2 mapping in patients with suspected myocarditis

Background The aim of this study was to test the interobserver variability of myocardial T1 and T2 Mapping prior to and T1 Mapping after the administration of contrast agent in patients with suspected myocarditis. The established methods for the detection of the presence of active inflammation - edema ratio (ER) and global relative enhancement (gRE) - require a “normal” reference region of interest (ROI) in adjacent skeletal muscle and depend on the choice of the muscle as well as its outline