Effect of carbon and nitrogen source on exopolysaccharide peptides production of Ganoderma lucidum in submerged culture

The purpose of this study is to discover high efficient and economical raw materials for commercial production of G.lucidum exopolysaccharide peptides(EPSP) in submerged culture.Twelve different souces(six carbon and six nitrogen sources) were used individually in 250 mL shake flask.The optimal carbon source was cornmeal for both EPSP production((2.664±0.801) g/L) and cell growth((4.559±0.150) g/L),the best nitrogen source was urea for EPSP production((0.636±0.040) g/L),and the most favorable nitrogen source was soybean powder for cell growth((2.222±0.256) g/L).Subsequently,the most advantageous combination in EPSP yield was cornmeal+soybean powder,which resulted in up to(4.366±0.434) g/L.The result of this study would be beneficial to industrial production of EPSP from G.lucidum.