Una visión de los linfomas cutáneos primarios de células B Primary Cutaneous B-cell Lymphomas

Summary Primary cutaneous B-cell lymphoma (PCBCL) represent a heterogeneous group of disease entities, they form part of the group of non-Hodgkin lymphomas and often have highly characteristics clinical and histological features, and a clinical behavior and prognosis, that are different from the primary nodal lymphomas of the same histologic subtype. In addition, differences in the pathogenesis, suggesting that primary cutaneous lymphomas should be considered as a distinctive group. The European Organization for Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Project Group has suggested a new organ-specific classification, however, the lack of consensus with the diagnostic criteria for the different entities that compose the group of the PCBCL has supposed that their classification will be a topic of continuous discussion and may lead to confusion among pathologists, hematologists, oncologists and dermatologists. In spite of the excellent forecast that present most of these lymphomas, the relapses occur frequently (30 to 60%), and thus ongoing follow-up is required and agreed treatment standards with the natural history of these malignances, these aspects are described in the present article.