Temporal changes of regional glucose use, blood flow and MAP2 immunostaining after hypoxia-ischemia in the immature rat brain 15

Background: In a situation with normal cerebral blood flow (CBF) and without increased energy utilization, increased glucose utilization (CGU) can be a sign of impaired mitochondrial metabolism, which may be an early step in the neurodamaging cascade during reperfusion after hypoxia-ischemia(HI).