Compound fluorescent micro-nano system and preparation method thereof based on one-pot process

2015 
The invention discloses a compound fluorescent micro-nano system and a preparation method thereof based on a one-pot process. A biomedical material with the matrix being butyl polyacrylate is constructed, wherein the entrapment component can be selected from fluorescent substances such as rhodamine, coumarin 6, nile red, camptothecin, adriamycin amycin and the like. The system disclosed by the invention is simple in preparation process, mild in condition, green and environment-friendly in process, less in energy consumption, free of pollution of three wastes, radiation, noise and the like and simple and convenient in separation and purification process. The obtained system is stable and easy to store and is a universal process for selectively preparing the compound fluorescent micro-nano system. Based on good biocompatibility and stability of the compound fluorescent micro-nano system as well as the fluorescence imaging and treating functions of the entrapment component, the system is expected to be relatively widely applied in the field of in vivo marking and tracing, biomedical imaging, targeted diagnosis and treat integration, medicine screening and optimization and the like and has good economic and social benefits in the field of life health and personal medical treatment and the like.
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