Vasovist ® in Lymphography

The lymphatic system is of paramount importance for the drainage of the interstitial fluid. Lymph nodes account for the enrichment of lymph fluid and play a central role in many diseases, especially in cancer. Due to its anatomical complexity, the lymphatic system has always been difficult to assess with imaging techniques. The combination of new contrast agents and advanced magnetic resonance imaging (MRI) techniques now permits semi-invasive assessment of both the lymphatic vessels and lymph nodes. Due to its transient and strong albumin binding, Vasovist® (Gadofosveset, Bayer Schering Pharma AG, Berlin, Germany) seems an ideal candidate for lymph node imaging.