Correlation between Longitudinal Strain and LVEDD in Children with isolatedSigniicant VSD at Children hospital Lahore.

Children presenting with significant VSD may have altered contractility of left ventricle. The volume load due to VSD causes remodeling and geometric structure change of left ventricle. Longitudinal Strain, and stain rate are new modalities which assess LV function in better way rather than LVEDD (left ventricular end diastolic dimensions). OBJECTIVE To evaluate the correlation of longitudinal strain with LVEDD in patients with isolated VSD through echocardiography. MATERIALS AND METHODS It was a cross sectional study using convenience sampling method. It used a Performa as a data-collecting tool after approval from ethical committee form October 2019. Data was collect from Cardiology Department of Children Hospital and Institute of Child Health Lahore. All the data was enter in SPSS version 25 software and then analyzed for statistically significant outcomes. Descriptive analysis was use to describe the basic features of the data, the chi-square test was used to measure the association among the different categorical variables. RESULTS 73 children of VSD were selected in the study. 53.4% were male and female were 46.6%. According to age breakdown, 32 children belong to 1 month to 5 years, 30 children were belong to 6 years to 10 years and 11 were from 11years to 15 years. LVEDD obtained in this study with mean of 34.98mm having positive correlation with the VSD sizes, which showed that LVEDD increase with increase in size of VSD. The average LV strain was -19.78 which is quite normal but in correlation with VSD size, it showed negative correlation showing LV strain decrease at some extent with increase in VSD sizes. CONCLUSION This recommends that contractility assessed by echocardiography did not change by a hemodynamically large VSD when assessed by longitudinal strain and stain rate.