TÜKÜRÜK BEZİNDE PLEOMORFİK ADENOMLARIN İNCELENMESİ, İNCE İĞNE ASPİRASYON SİTOLOJİSİNİN DOKU BİYOPSİSİ İLE KORELASYONU

AMAC: Pleomorfik adenom, tukuruk bezinin en sik gorulen tumorudur fakat  tumorun ozelliklerini yansitan cok az sayida calisma bulunmaktadir. Amacimiz bu tumorun histopatolojik ve klinikopatolojik ozelliklerini incelemek ayrica ince igne aspirasyon sitolojisinin ozelliklerini ve doku biopsisi ile uyumunu arastirmak. GEREC VE YONTEM: Pleomorfik adenom tanisi alan 85 olgu incelendi. Olgularin demografik ozellikleri, klinikopatolojik ozellikleri ve operatif verileri retrospektif olarak kaydedildi. Operasyondan onceki  IIAB sonuclari dokumante edildi ve IIAB sonuclarinin doku biopsisi ile uyumu degerlendirildi. BULGULAR: Olgularimizda erkek-kadin orani: 1/1.96 ve yas ortalamasi 44.45 idi (11-87). Olgularimizin cogu 40-59 yas araligindaydi (%41.57). Tumor en fazla (%59) parotis bezinde, 2. siklikta (%18) minor tukuruk bezlerinde goruldu. Ortalama tumor capi 3.23 cm idi (1-9 cm) ve tumor capi en sik (%57.30) 2-4 cm araligindaydi. Klasik tip en fazla gorulen (%94.4) histolojik tipti. Rekurrens benign olgularin sadece 1’inde (%1.40) goruldu. Tumorde malign transformasyon olgularimizin 5’inde (% 5.61) vardi. Operasyondan once yapilan IIAB ile %80.32 gibi yuksek oranda PA tanisi verilmisti. SONUC : Pleomorfik adenom en fazla parotis bezinde gorulur ve burada da cogunlukla yuzeyel  lobda yerlesir. 4.-5. dekadlarda ve kadin cinsiyette daha siktir. Tumor capi 2-4 cm araliginda daha fazla gorulur. Tumorun dusuk oranda nuks ve  malign transformasyon olasiligi vardir. Preoperatif IIAB’nin tanisal dogrulugu oldukca yuksektir ve IIAB yapilmasi dogru tedavi yaklasimi acisindan cok onemlidir. ANAHTAR KELIMELER: pleomorfik adenom, tukuruk bezi, tumor, IIAB ABSTRACT OBJECTIVE: Pleomorphic adenoma is the most common tumor of the salivary gland but there are very few studies that reflect the characteristics of the tumor. Our aim is to investigate the histopathological and clinicopathological features of this tumor and to investigate the characteristics of fine needle aspiration cytology and its compatibility with tissue biopsy. MATERIAL AND METHODS: 85 cases with pleomorphic adenoma were evaluated. The demographic characteristics, clinicopathological features and operative data of the patients were recorded retrospectively. The results of FNAB before the operation were documented and the compliance of FNAB results with tissue biopsy was evaluated. RESULTS: The male to female ratio in our patients was 1/1.96 and the mean age was 44.45 (11-87). Most of our cases were in the 40-59 age range (41.57%). The tumor was seen in the parotid gland in the majority (59%) and in the minor salivary glands in the 2nd order (18%). The mean tumor diameter was 3.23 cm (1-9 cm) and the tumor diameter was most frequent (57.30%) in the range of 2-4 cm. The classical type was the most common (94.4%) histological type. Recurrence was seen in only 1 (1.40%) of benign cases. Malignant transformation in the tumor was present in 5 (5.61%) cases. The diagnosis of PA was as high as 80.32% with preoperative FNAB. CONCLUSIONS : Pleomorphic adenoma is most often seen in the parotid gland and is usually located in the superficial lobe. It is more frequent in the 4th to 5th decade and in the female gender. Tumor diameter is more in the range of 2-4 cm. The tumor has a low rate of recurrence and malignant transformation. Preoperative FNAB has a high diagnostic accuracy and FNAB is very important for the correct treatment approach. KEYWORDS : Pleomorphic adenoma, salivary gland, tumor, FNAB