Evolution of the Cryo-lesion

Expected results after freezing are erythema, urtication, and edema which may last for several days. If freezing is superficial, vesicles or bullae developed. Bullae may become hemorrhagic. When treating malignances, a more gelatinous appearance may result. The stroma is more resistant to freezing than the cellular elements. Healing for most lesions takes place within 2 weeks for benign or premalignant lesions to 4–6 weeks for malignant lesions. Systemic steroids may be used to prevent swelling around the periorbital area.