Platelet Deposition in Renal Transplant Rejection and Treatment with Prostacyclin Infusion

Platelet deposition on vascular endothelium is well known to play a key role in transplant rejection. Colman and co-workers1 and Smith and co-workers2 have described this phenomenon in acute and subacute rejection, whereas Leithner and coworkers3 observed platelet deposition by a radioisotopic method in the majority of patients suffering from chronic rejection too.