Lack of effect of high-intensity pulsed ultrasound on sister chromatid exchange and in vitro chinese hamster ovary cell viability

Abstract The frequency of sister chromatid exchanges (SCEs) in in vitro Chinese hamster ovary cells and their viability were not affected by 3-min exposures to 2–4 MHz, focused, pulsed ultrasound with a pulse repetition rate of 200 Hz, pulse duration of 10 μsec and intensities (SPTP) of 500 W/cm 2 and 2500 W/cm 2 . The viability results are consistent with those reported elsewhere; the SCE response does not verify a specific previously reported positive response.