Progress in recent development of stereoselective synthesis of β2-amino acid derivatives from β-nitroacrylate derivatives

The synthesis and properties of β-amino acids have drawn considerable attention owing to their ubiquitous presence in naturally occurring products of biological importance. While β3-amino acids are readily available from α-amino acids via one-carbon homologation, synthesis of β2-amino acids generally requires multistep efforts. This review punctuates on the recent accomplishments in the synthesis of β2-amino acids and their derivatives from substituted β-nitropropionate analogs obtained from stereoselective transformations of β-nitroacrylates.