Multi-shell rhzomorph derivative, preparation and uses thereof

2009 
The invention discloses a myriocin derivative and a preparation method thereof. The preparation method comprises the following steps: 9-fluorenylmethoxycarbonyl chloride is added to myriocin under the condition that pyridine and tetrahydrofuran solution provide a reaction environment, the 9-fluorenylmethoxycarbonyl chloride reacts with the myriocin to generate the myriocin derivative, the derivative introduces a group with ultraviolet characteristic absorption peaks to amino groups of the myriocin, and quantitative analysis can be carried out by high performance liquid chromatography, thus further quantitatively characterizing the myriocin. The method has reliable and accurate determination results, and can be used for determining myriocin content of traditional Chinese herbal medicines such as cicada fungus, Chinese caterpillar fungus and the like, determining preparations containing the cicada fungus or the Chinese caterpillar fungus and extracts thereof, and determining the myriocin content of biological samples.
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