Abstract 12089: Dual Actions of β2AR-Agonism Confer Protection Against Heart Failure and Renal Dysfunction via Inotropic and Lusitropic Effects and Normalized Cholesterol Homeostasis in a Mouse Model of Alport Syndrome

Ahmed Chahdi,Keyvan Yousefi,José Manuel Condor Capcha,Camila Iansen Irion,Guerline Lambert,Serene A. Shehadeh,Julian C. Dunkley,Yee-Shuan Lee,Aisha Khan,Melina Ramic,Nadja S. Andrade,Zane Zeier,Derek M. Dykxhoorn,Chryso Katsoufis,Michael Freundlich,Joshua M. Hare,Mary B. Nabity,Carolina Rivera,Anastasios Lymperopoulos,Keith A. Webster,Noam Zelcer,Lina A. Shehadeh

Abstract 12089: Dual Actions of β2AR-Agonism Confer Protection Against Heart Failure and Renal Dysfunction via Inotropic and Lusitropic Effects and Normalized Cholesterol Homeostasis in a Mouse Model of Alport Syndrome

2021

Introduction: Col4a3-/- Alport mice present a model of heart failure with preserved ejection fraction (HFpEF) secondary to chronic kidney disease(CKD) wherein etiological relationships have been es...

Keywords:

Cardiology
Heart failure with preserved ejection fraction
Lusitropy
Renal function
Internal medicine
Inotrope
Heart failure
Medicine
Alport syndrome
Kidney disease
Cholesterol

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