Properties of α-l-iduronidase in cultured skin fibroblasts from α-l-iduronidase-deficient patients
1984
On DEAE cellulose column chromatography, α-l-iduronidase in cultured skin fibroblasts was resolved into two distinct components, forms A and B. They had similar Km values for 4-methylumbelliferyl-α-l-iduronide, but differed in pH optima and thermal stability. Form B was more heat-stable than form A.
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