Modelling of blood pressure and total cardiovascular risk outcomes after second-line valsartan therapy: The BSCORE study Modélisation de la pression artérielle et du risque cardiovasculaire total après traitement de deuxième ligne par valsartan : l'étude BSCORE

Summary Background. — European guidelines recommend that antihypertensive management should be graded as a function of total cardiovascular risk. Aims. — To examine the multilevel (patient- and physician-level) determinants of blood pressure and residual total cardiovascular risk outcomes associated with second-line valsartan therapy. Methods. — The BSCORE study was a prospective, multi-centre, pharmacoepidemiological study of the ‘‘real-world’’ effectiveness of second-line valsartan with or without hydrochlorothiazide.