Nadir görülen bir ülseratif kolit komplikasyonu: Piyoderma gangrenosum

Pyoderma gangrenosum is a rare inflammatory skin illness characterized by ulcers. It can be seen with unknown etiology or with some systemic disorders such as ulcerative colitis, Crohn's disease and monoclonal gammopathy. Ulcers may be seen as single or multiple. We present in this article a pyoderma gangrenosum case that occurred with the activation of ulcerative colitis. A 21-year-old male was admitted to our hospital with a one-month history of symptoms of bloody and mucoid defecation with general intense body pain, ulcers (some with purulent secretion) and necrotic wounds. Rectosigmoidoscopy showed active state ulcerative colitis, and this diagnosis was confirmed with biopsies. Amebiasis was excluded with stool examination. After exclusion of infectious causes with gram staining and culture, the patient was diagnosed as pyoderma gangrenosum with histopathological findings. We started high-dose corticosteroid with the diagnosis of pyoderma gangrenosum and ulcerative colitis. Symptoms and findings significantly regressed in 10 days and totally healed in three months. In conclusion, pyoderma gangrenosum (which rarely occurs and usually does not correlate with the disease activity) can be seen with disease activity and may heal with high-dose steroid treatment in a short time.