Expression of GHR and Downstream Signaling Genes in Human Adipose Tissue—Relation to Obesity and Weight Change

Camilla A M Glad,Per-Arne Svensson,Fredrik Nyström,Peter Jacobson,Lena M.S. Carlsson,Gudmundur Johannsson,Johanna C. Andersson-Assarsson

Expression of GHR and Downstream Signaling Genes in Human Adipose Tissue—Relation to Obesity and Weight Change

2019

Camilla A M Glad
Per-Arne Svensson
Fredrik Nyström
Peter Jacobson
Lena M.S. Carlsson
Gudmundur Johannsson
Johanna C. Andersson-Assarsson

Context: GH is a strong regulator of metabolism. In obesity, both GH secretion and adipose tissue GHR gene expression are decreased. More detailed information on the regulation of GHR, STAT3/5, and ...

Keywords:

Obesity
Endocrinology
Internal medicine
Gene
Upstream and downstream (transduction)
Adipose tissue
Growth hormone receptor
Medicine
growth hormone secretion
Adipocyte
STAT5A
weight change
STAT3
Gene expression

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