Age influences the effects of nicotine and monoamine oxidase inhibition on mood-related behaviors in rats
2010
Rationale
Epidemiological studies have demonstrated a comorbidity of smoking with depression and anxiety, particularly during adolescence. However, few animal studies have considered possible synergistic interactions between nicotine and other tobacco smoke constituents, such as monoamine oxidase (MAO) inhibitors, in the regulation of mood.
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