Triple helix forming oligonucleotides

Foreword. Section I: Background and Structural Aspects. 1. The Antigene Strategy: Progress and Perspectives in Selective Gene Silencing C. Helene. 2. Triple-Helix Structure. The Triple-Helix-Forming Oligonucleotide H. Porumb. 3. Thermodynamic State Diagrams of Oligonucleotide Triple Helices G.E. Plum, K.J. Breslauer. 4. Imaging of Triplexes by Electron and Scanning Force Microscopy D. Cherny. 5. Chemical Modifications of Triple Helix Forming Oligonucleotides U. Asseline. 6. Triple Helix Formation with Modified Oligonucleotides S.M. Gryaznov. 7. Oligonucleotides as Artificial DNases V. Zarytova, A. Levina. Section II: The Biology of Triple Helices. 8. Potential Mechanisms of Action L.J. Maher. 9. Oligonucleotide Uptake and Delivery in Tissue Culture Cells S.W. Ebbinghaus, et al. 10. Triple-Stranded Complexes as Antigene Molecules: Transcription Inhibition Ex Vivo C. Giovannangeli. 11. Gene-Targeting Triple Helix Forming Purine Oligonucleotides F. Svinarchuk, C. Malvy. 12. DNA Triple Helix as a Tool to Regulate Cytokine Gene Expression M. Kochetkova, M.F. Shannon. 13. Genome Modification by Triplex-Forming Oligonucleotides K.M. Vasquez, P.M. Glazer. 14. Psoralen-Coupled Oligonucleotides: In Vivo Binding and Repair F.-X. Barre, et al. 15. Structure and Biology of H DNA S.M. Mirkin. 16. Triplex-Binding Proteins A.-L. Guieysse, D. Praseuth. 17. RNA and Triple Helices Kyonggeun Yoon, etal. Section III: New Developments and Applications. 18. Triplexes Involving PNA T. Bentin, P.E. Nielsen. 19. Triple Helix Stabilizing Agents C. Escude, T. Garestier. 20. New Targets for Triple Helix Forming Oligonucleotides J.S. Sun. 21. Triplexes and Biotechnology M.D. Frank-Kamenetskii. Index.