HETEROPOLYACIDES AS GREEN AND REUSABLE CATALYSTS FOR THE SYNTHESIS OF (3,4-b)(1,3,4) THIADIAZINES

Synthesis of [3,4- b ][1,3,4]thiadiazines from the condensation of 4-amino-6-methyl-3-thioxo-1,2,4-triazine-5(2 H )-one (AMTTO) or 4-amino-1,4-dihydro-5-methyle-1,2,4-triazole-5-thione (AMTT) with phenacyl bromide in the presence of a catalytic amount of various heteropolyacids (HPAs) under refluxing conditions is reported. KEY WORDS : Heteropolyacids, Phenacyl bromide, Heterocyclization, Thiadiazines Bull. Chem. Soc. Ethiop. 2014 , 28(1), 67-71. DOI: http://dx.doi.org/10.4314/bcse.v28i1.8