A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells

TacGhee Yi,Yun Kyoung Cho,Hyun-Joo Lee,Junghee Kim,Myung-Shin Jeon,Dong-Sik Ham,Woo Cheol Kim,Sun U. Song

A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells

2019

TacGhee Yi
Yun Kyoung Cho
Hyun-Joo Lee
Junghee Kim
Myung-Shin Jeon
Dong-Sik Ham
Woo Cheol Kim
Sun U. Song

Background and Objectives Mesenchymal stem cells (MSCs) are used to treat autoimmune or inflammatory diseases. Our aim was to determine the immunomodulatory mechanisms elicited by MSCs during inflammation.

Keywords:

Bone marrow
Acetylcholine
Cell biology
Mesenchymal stem cell
Chemistry
Nicotinic agonist
Immune system
Pharmacology
Mixed lymphocyte reaction
Inflammation
Peripheral blood mononuclear cell
lymphocyte proliferation

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