Method for preparing a 17α- hydroxy steroid ester

The present invention discloses a method for preparing steroids, particularly it relates to a method for preparing 17α- hydroxy steroid esters of the present invention will 17α, 21- dihydroxy steroid ester to react with the original form containing 1,3 - dioxan-5-one ring of the steroid intermediate, and then to give 17α- hydroxy steroid ester by hydrolysis. Compared with the prior art, the present invention effectively avoids the use of strong irritant trifluoroacetic anhydride, mild reaction conditions, hydrolysis of the solid acid catalyst may be employed, with an acid catalyst is recycled and are environmentally friendly, low pollution process simple, mild reaction conditions suitable for industrial production.