Value of prostate MRI in determining appropriate candidates for active surveillance.

109 Background: The objective was to measure the added benefit of multi-parametric endorectal coil prostate MRI (eMRI) to traditional active (AS) criteria in delineating men with more advanced disease. Methods: We performed a retrospective study of 115 men who underwent robot-assisted laparoscopic prostatectomy (RALP) for their CaP with whole-mount pathological evaluation. All men underwent eMRI for surgical planning—including T2 weighted, diffusion-weighted (DWI), dynamic contrast-enhanced (DCE), and MR Spectroscopy—between July 2008 and March 2011. We examined the diagnostics of Epstein’s criteria (E-AS) for clinically insignificant CaP or in combination with MR parameters (eMRI-AS criteria) in predicting more advanced disease. E-AS criteria included Gleason score (GS) 3+3=6, 0.85x10-3 mm2/sec, Ktrans 1.5 Hz, and normal MRSI defined the eMRI-AS cohort. Outcomes were st...