First total synthesis of antimalarial (+)-cryptorigidifoliol A
2015
Abstract The first total synthesis of antimalarial (+)-cryptorigidifoliol A was accomplished by two different approaches in 6 and 5 steps with overall yields of 45% and 33%, respectively. Double asymmetric allylations and ring-closing metathesis reaction in route A, Prins, and RCM in route B were used as key steps.
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