Exploitation of revered potent medicinal mushroom Ganoderma lucidum with particular accent on oncotherapeutics

Abstract From the time immemorial, Ganoderma lucidum generally called as Reishi, is utilized as healthcare constituent, well-being, and longevity in developing countries. It is a basidiomycete rot fungus thus, most important resource for the manufacture of innate fungal medicines. Because of its medicinal value Ganoderma has been utilized for the cure and healing of different diseases for several years. With the use of murine and human cell lines on anticancer characteristics of G. lucidum have been verified by numerous studies, both in vitro and in vivo examinations. Rigorous investigations proved that G. lucidum presents a range of pharmacological active constituents, namely, anticancer, cardioprotective, hepatoprotective, antioxidant, immune modulatory, antihypertensive, and antidiabetic, etc. Furthermore, these experimented anticancer constituents extracted from Ganoderma have encouraged its convention to cancer patients together with chemotherapy. Discovery of innate resource proposed for new and fresh bioactive composites proved to be a promising source of drugs over the ancient times, presenting medicines or lead compounds of substantial remedial prospective. Ganoderma is found to have wide-ranging relevance for curing cancer through the immune system regulation. Ganoderma exercises multiple mechanisms for the destruction of cancer cells and perhaps has probable curative exercise for the anticipation as well as management of the deadly disease. This book chapter is designed to assist the communities improved understanding of variety and prospective of macro fungi paving way to additional systematic examination and therefore, extra-efficient management and employment.