Tinidazole injection preparation and preparation method thereof

2013 
The invention discloses a tinidazole injection preparation which consists of the following components by weight percent: 0.3-0.8% of tinidazole, 0.9% of an osmotic pressure regulating agent, 0.25-0.5% of an absorbing agent, and the balance of injection water to achieve 100%, wherein pH value is regulated to be 4.0-4.2 through a pH regulating additive. Furthermore, the invention discloses a preparation method of the tinidazole injection preparation. According to the tinidazole injection preparation and the preparation method thereof, problems of high raw material consumption and low qualification rate of the tinidazole injection in production process can be effectively solved, so that an expected effect is achieved. According to the tinidazole injection preparation and the preparation method, by regulating dosages and percents of the absorbing agent and the osmotic pressure regulating agent in the formula as well as regulating main drug dissolving temperature and two absorbing time limits of the absorbing agent, the quality of a product can effectively guaranteed, and the production cost is reduced. And the tinidazole injection preparation disclosed by the invention is simple in formula, high in yield, and stable and reliable, and can implement industrial mass production conveniently.
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