Comparison of 320-Row Computed Tomography Coronary Angiography With Conventional Angiography for the Assessment of Coronary Artery Disease With Different Atherosclerotic Plaque Characteristics

Objective: The objective of this study was to compare the accuracy of 320-row computed tomography angiography (CTA) with conventional coronary angiography. Methods: Two hundred seventy-four patients with coronary artery disease who received both invasive coronary angiography and 320-row CTA were included. Stenosis of 50% or greater was considered obstructive. Results: In patient-based analysis, accuracy of CTA was 89.4%, with sensitivity of 94.6% and specificity of 54.3%. In segment-based analysis, the overall (4110 segments) accuracy of CTA was 90.7%, with sensitivity of 66.5% and specificity of 95.8%. For the segments with plaques (1191 segments), accuracy of CTA was 80.1%, with sensitivity of 83.5% and specificity of 77.0%. For segments with no plaque (2919 segments), accuracy of CTA was 95.0%, with sensitivity of 0.7% and specificity of 100.0%. For the segments with stents (110 segments), the accuracy of CTA was 86.4%. Conclusions: A 320-row CTA has potential to detect coronary lesions with soft and intermediate plaques.